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Amyloid arthropathy presenting as symmetrical polyarthritis

Authors

  • Laxmi Patil
  • Jyotsna Oak

DOI:

https://doi.org/10.15305/ijrci/v4i1/181

Keywords:

Amyloid arthropathy, symmetrical polyarthritis, spondyloarthritides, rheumatoid arthritis, RA

Abstract

The present case study deals with two cases of symmetrical polyarthritis mimicking rheumatoid arthritis. Autoantibodies and rheumatoid factor were negative in both the cases and subtle clinical findings led to the diagnosis. The former patient was diagnosed with primary amyloidosis-related arthropathy and the latter with multiple myeloma-related amyloid arthropathy.

References

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Wiernik PH. Amyloid joint disease. Medicine (Baltimore) 1972;51:465–479.

Hickling P, Wilkins M, Newman GR, Pritchard MH,Jessop J, Whittaker J, Nuki G. A study of amyloid arthropathy in multiple myeloma. Q J Med 1981;50:417–433.

Comenzo RL. Primary systemic amyloidosis. Curr Treat Options Oncol 2000;1:83–89.

Kyle RA, Gertz MA. Primary systemic amyloidosis: clinical and laboratory features in 474 cases. Semin Hematol 1995;32:45–59.

Gillmore JD, Lovat LB, Persey MR, Pepys MB, Hawkins PN. Amyloid load and clinical outcome in AA amyloidosis inrelation to circulating concentration of serum amyloid Aprotein. Lancet 2001;358:4–5.

Hou FF, Reddan DN, Seng WK, Owen WF Jr. Pathogenesis of beta(2)-microglobulin amyloidosis: role of monocytes/macrophages. Semin Dial 2001;14:135–139.

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Published

2016-04-25

Issue

Vol. 4 No. 1 (2016)

Section

Case Studies